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Image Search Results
Journal: Frontiers in Microbiology
Article Title: Novel gold(III)-dithiocarbamate complex targeting bacterial thioredoxin reductase: antimicrobial activity, synergy, toxicity, and mechanistic insights
doi: 10.3389/fmicb.2023.1198473
Figure Lengend Snippet: Development of resistance to complex 2 in (A) MRSA 1620579-000 strain and (B) A. baumannii AbCr17 strain with daptomycin (DAP) and colistin (CST) controls, respectively. The y axis shows the fold increase in the MIC value after each daily serial passage compared to the parental strain. For DAP, the highest concentration tested was 256x MIC, and for CST, the highest concentration tested was 2048x MIC. Graphs are representative of two independent experiments.
Article Snippet: The antibiotics used in the experiments were auranofin (Cayman Chemical), amikacin (AMK, AlfaAesar), ampicillin (AMP, SigmaAldrich), colistin (CST, MPBiomedicals), ciprofloxacin (CIP, SigmaAldrich),
Techniques: Concentration Assay